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Diazepam may be administered intravenously or intramuscularly (deep into the muscle). However, absorption following I.M. administration is slow and erratic; thus, this route of administration should be avoided if possible.
Diazepam is used to treat anxiety, muscle spasms, and alcohol withdrawal. The injection form is used when prompt relief is desired or when the medication cannot be taken by mouth. This medication is also used for the short-term treatment of serious seizures that do not stop (status epilepticus).
Description
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect. Wikipedia
Formula: C16H13ClN2O
Elimination half-life: (50 hours); 20–100 hours (36–200 hours for main active metabolite desmethyldiazepam)
Bioavailability: 76% (64–97%) by mouth, 81% (62–98%) rectal
Excretion: Kidney
Addiction liability: Moderate
ATC code: N05BA01 (WHO)
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